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CX 04328

CAS No. 957890-42-5

CX 04328 ( LEDGIN-6 )

Catalog No. M16841 CAS No. 957890-42-5

CX 04328 (LEDGIN-6) is an allosteric HIV-1 integrase inhibitor that inhibits the LEDGF/p75-integrase interaction with IC50 of 1.37 uM.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    CX 04328
  • Note
    Research use only, not for human use.
  • Brief Description
    CX 04328 (LEDGIN-6) is an allosteric HIV-1 integrase inhibitor that inhibits the LEDGF/p75-integrase interaction with IC50 of 1.37 uM.
  • Description
    CX 04328 (LEDGIN-6) is an allosteric HIV-1 integrase inhibitor that inhibits the LEDGF/p75-integrase interaction with IC50 of 1.37 uM, antiviral activity EC50 of 2.35 uM.
  • Synonyms
    LEDGIN-6
  • Pathway
    Microbiology/Virology
  • Target
    HIV
  • Recptor
    HIV
  • Research Area
    Infection
  • Indication
    ——

Chemical Information

  • CAS Number
    957890-42-5
  • Formula Weight
    353.85
  • Molecular Formula
    C21H20ClNO2
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO : ≥ 100 mg/mL 282.61 mM; H2O : < 0.1 mg/mL
  • SMILES
    CCCC(C1=C(C2=CC=CC=C2)C3=CC(Cl)=CC=C3N=C1C)C(O)=O
  • Chemical Name
    2-(6-chloro-2-methyl-4-phenylquinolin-3-yl)pentanoic acid

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Christ F, et al. Nat Chem Biol. 2010 Jun;6(6):442-8.
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